Oxygen Transport Blood Buffers  Elmhurst College
Carbon Dioxide Transport Respiratory Acidosis Metabolic Acidosis  Chemistry Department
Buffers in the Kidenys Respiratory Alkalosis Metabolic Alkalosis  Virtual ChemBook

Hemoglobin - Oxygen Equation:

HHgb + O 2 <===> HgbO 2 + H+

Blood Buffer Equation:

CO2 + HOH <===> H2CO3 <===> H+ + HCO3-

Metabolic Acidosis

.QUES. 6: Case 2:
Uncompensated Laboratory Results: pH =7.1, pCO2 = 42, HCO3- = 12.

a. List the condition - acidosis or alkalosis, metabolic or respiratory, compensated or uncompensated.

pH =7.1 = acidosis, uncompensated
pCO2 = 42 = metabolic, uncompensated
HCO3- = 12 = metabolic

b. What is the primary cause of the condition?

Could be deficit of bicarbonate caused by diarrhea

c. Explain the other lab results using the primary cause and equilibrium principles.

Equilibrium: CO2 + HOH === H2CO3 === H+ + HCO3-

If the bicarbonate is lower than normal, than the equilibrium has shifted to the right, which increases hydrogen ions, and decrease the pH.

d. State and explain how the compensation will return pH to normal.

The table says that the compensation is for the lungs to blow off carbon dioxide by hyperventilation. This means that the carbon dioxide will be lower in the blood as a result. If carbon dioxide is decreased, then the equilibrium shifts left, which decreases the hydrogen ions, which increases the pH more toward normal.

e. Explain how the treatment with __?___ will work.

The suggested treatment is to give an IV with sodium bicarbonate. If bicarbonate is increased, then the equilibrium shift left, which decrease the hydrogen ion concentration, which increase the pH more toward normal.